The Phospho-TDP-43/TARDB-S409/S410 Antibody (CABP1241) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for detecting phosphorylated TDP-43 at serine 409 and serine 410 residues in human samples.TDP-43 is known to play a crucial role in RNA processing and regulation, and abnormal phosphorylation of TDP-43 has been implicated in the pathogenesis of ALS and FTD. The CABP1241 antibody is validated for use in Western blot applications, providing researchers with a powerful tool for studying the phosphorylation status of TDP-43 in various biological contexts.
This antibody is validated for use in WB, ELISA, DB applications and has demonstrated reactivity against Human samples.
Product Name:
Phospho-TDP-43/TARDB-S409/S410 Antibody
SKU:
CABP1241
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:
SKSS GW
Tested Applications:
WBELISADB
Recommended Dilution:
WB
1:500 - 1:2000
DB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ALS10, TDP-43, Phospho-TDP-43/TARDBP-S409/S410
Cellular Localization:
Nucleus.
Calculated MW:
45kDa
Observed MW:
Refertofigures
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Purification Method
Affinity purification
Gene ID
23435
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Dot-blot analysis of all sorts of peptides using Phospho-TDP-43/TARDB-S409/S410 antibody (CABP1241) at 1:1000 dilution. Exposure time: 1s.
Dot-blot analysis of all sorts of peptides using Phospho-TDP-43/TARDB-S409/S410 antibody (CABP1241) at 1:1000 dilution. Exposure time: 10s.
