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APC Anti-Rat CD3 Antibody [G4.18] (AGEL2460)

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SKU AGEL2460
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Rat
Host Species Mouse
Isotype Mouse IgG3, κ
Clone G4.18
Conjugation APC
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Description

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APC Anti-Rat CD3 Antibody [G4.18]

The APC Anti-Rat CD3 Antibody (G4.18) is a potent tool for researchers studying immune responses and T cell activation in rats. This monoclonal antibody, clone G4.18, is specifically designed to target CD3, a crucial protein complex found on the surface of T cells. By binding to CD3, this antibody allows for the detection and analysis of T cell populations in rat samples, making it an essential reagent for immunology and transplantation studies.The APC Anti-Rat CD3 Antibody (G4.18) is highly specific and has been validated for use in flow cytometry applications, enabling researchers to accurately identify and quantify CD3-expressing T cells in their experimental samples.

The antibody's strong reactivity and reliability make it a valuable tool for investigating T cell-mediated immune responses, tolerance induction, and immune cell profiling in rat models.By targeting CD3, the APC Anti-Rat CD3 Antibody (G4.18) provides researchers with a powerful means to study T cell activation, proliferation, and function in a rat experimental system. Its precise specificity and consistent performance make it an indispensable tool for advancing our understanding of immune responses and developing new therapeutic approaches for immune-related diseases.

Product Title:APC Anti-Rat CD3 Antibody [G4.18]
SKU:AGEL2460
Size:25µg, 100µg
Clone No:G4.18
Synonyms:T-cell surface glycoprotein CD3 δ; γ; ε; and ζ chains;CD3 Complex; T3;CD3;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG3, κ
Isotype Control:APC Mouse IgG3, κ Isotype Control[A112-3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P19377 Q64159 D4A5M2
Gene ID:25710,300678,315609,25300
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.

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