The Beclin 1 Antibody (CAB17028) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. It specifically binds to the BECN1 protein, enabling precise detection and analysis in a variety of cell types.BECN1, also known as Beclin 1, is a critical player in the autophagy pathway, which is responsible for degrading and recycling cellular components to maintain cellular health and function. Dysregulation of autophagy has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Beclin 1 Antibody
SKU:
CAB17028
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
8678
RRID
AB_2768591
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Beclin 1 Rabbit pAb (CAB17028) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
