The BRD1 Polyclonal Antibody (CAB9869) is a powerful tool for researchers studying the BRD1 protein, which plays a key role in epigenetic regulation and gene expression. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting BRD1 in human samples. Validated for use in Western blot applications, this antibody enables researchers to visualize and analyze BRD1 in a variety of cell types.BRD1 is a member of the bromodomain-containing protein family, known for its involvement in chromatin remodeling and transcriptional regulation. Dysregulation of BRD1 has been linked to various diseases, including cancer, neurological disorders, and developmental abnormalities.
By investigating the function of BRD1, researchers can gain insights into the underlying mechanisms of these conditions and potentially discover new therapeutic interventions.In summary, the BRD1 Polyclonal Antibody is a valuable tool for exploring the biological roles of BRD1 and its potential implications in disease pathogenesis. Its specificity and versatility make it an excellent choice for immunology and cancer research studies aiming to uncover the complex functions of the BRD1 protein.
Product Name:
BRD1 Rabbit Polyclonal Antibody
SKU:
CAB9869
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human BRD1 (NP_055392.1).
This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schizophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23774
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BRD1 antibody (CAB9869) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
