Description
Cathepsin L Inhibitor Screening Kit (Fluorometric)
Cathepsin L (CTSL, EC 3.4.22.15) is a lysosomal cysteine protease that is implicated in protein degradation, arthritis, apoptosis, and cancer. Assay Genie's Cathepsin L Inhibitor Screening Kit utilizes the ability of active Cathepsin L to cleave the synthetic AFC-based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin L inhibitor, the cleavage of this substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize potential inhibitors of Cathepsin L.
Figure: Inhibition of Cathepsin L activity by CTSL Inhibitor. Assay was performed following the kit protocol.
Key Information | Description |
Product SKU | BN00441 |
Size | 100 assays |
Detection Method | Fluorescence (Ex/Em 400/505 nm) |
Applications | Screen/study/characterize potential inhibitors of Cathepsin L |
Features and Benefits |
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Kit Components |
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Storage Conditions | -20°C |
Shipping Conditions | Gel Pack |
USAGE | For Research Use Only! Not For Use in Humans. |