The C/EBPB Monoclonal Antibody (CAB19538) is a high-quality antibody developed for reliable detection and analysis of target proteins. With its high specificity and sensitivity, this antibody is ideal for use in various applications such as Western blotting, immunohistochemistry, and flow cytometry.CEBP Beta is a transcription factor that plays a crucial role in regulating gene expression related to immune responses, cellular differentiation, and metabolism. Dysregulation of CEBP Beta has been linked to various diseases, including cancer, inflammatory disorders, and metabolic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
C/EBPB Monoclonal Antibody
SKU:
CAB19538
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC0017
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TCF5, IL6DBP, NF-IL6, C/EBP-beta, C/EBPB
Positive Sample:
HeLa
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
36kDa
Observed MW:
46kDa(LAP)/48kDa(Full-length)
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions.
Purification Method
Affinity purification
Gene ID
1051
RRID
AB_2862655
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using C/EBPB Rabbit mAb (CAB19538) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): TT. Exposure time: 20 s.
