Description
system_update_altDatasheet
| Product name | Human TRPA1 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP016 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | TRPA1 |
| Uniprot: | O75762 |
| Description: | Human TRPA1 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length TRPA1 protein has a MW of 127.5 kDa |
| Protein Family: | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
| Protein Pathways: | |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | ANKTM1; FEPS; FEPS1 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | The structure of the protein is highly related to both the protein ankyrin and transmembrane proteins. This protein is activated by a large variety of structurally unrelated electrophilic and non-electrophilic chemical compounds. Electrophilic ligands activate TRPA1 by interacting with critical N-terminal Cys residues in a covalent manner, whereas mechanisms of non-electrophilic ligands are not well determined. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system. |
| Delivery: | In Stock |
| Usage | Research use only |
