The Cytochrome P450 4A (CYP4A11) Monoclonal Antibody (CAB19662) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through rabbit immunization, displays high reactivity towards human samples and has been validated for Western blot applications.CYP4A11 is known for its involvement in the metabolism of fatty acids, steroids, and eicosanoids, making it a key player in lipid homeostasis and inflammation regulation. Its dysregulation has been linked to various diseases, including cardiovascular disorders, diabetes, and cancer.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Cytochrome P450 4A (CYP4A11) Monoclonal Antibody
SKU:
CAB19662
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2219
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. Multiple transcript variants have been found for this gene.
Purification Method
Affinity purification
Gene ID
1579
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Cytochrome P450 4A (CYP4A11) (CYP4A11) Rabbit mAb (CAB19662) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Immunohistochemistry analysis of paraffin-embedded Rat kidney tissue using Cytochrome P450 4A (CYP4A11) Rabbit mAb (CAB19662) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Human liver tissue using Cytochrome P450 4A (CYP4A11) Rabbit mAb (CAB19662) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
