DYNLT1 Rabbit Polyclonal Antibody (CAB4150)
- SKU:
- CAB4150
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | DYNLT1 Rabbit Polyclonal Antibody |
SKU: | CAB4150 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human DYNLT1 (NP_006510.1). |
Sequence: | MEDY QAAE ETAF VVDE VSNI VKEA IESA IGGN AYQH SKVN QWTT NVVE QTLS QLTK LGKP FKYI VTCV IMQK NGAG LHTA SSCF WDSS TDGS CTVR WENK TMYC IVSA FGLS I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | CW-1; TCTEL1; TCTEX1; tctex-1; DYNLT1 |
Positive Sample: | 293T,MCF7,Mouse thymus,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, cytoskeleton, spindle. |
Calculated MW: | 12kDa |
Observed MW: | 13kDa |
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 6993 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |