The ERMAP Polyclonal Antibody (CAB10425) is a valuable tool for researchers studying ERMAP, a protein involved in red blood cell development and function. This antibody, produced in rabbits, is highly specific to ERMAP in human samples and has been validated for use in Western blot applications. By binding to the ERMAP protein, this antibody enables the detection and analysis of ERMAP expression in a variety of cell types, making it ideal for studies in hematology and related fields.ERMAP, also known as erythroblast membrane-associated protein, plays a crucial role in erythropoiesis and red blood cell maturation.
Dysregulation of ERMAP expression has been linked to various hematologic disorders, making it a promising target for research aimed at understanding and treating conditions such as anemia and hemolytic diseases. By studying ERMAP, researchers can gain insights into the mechanisms underlying red blood cell development and function, paving the way for new therapeutic strategies in the treatment of blood disorders.
Product Name:
ERMAP Rabbit Polyclonal Antibody
SKU:
CAB10425
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-155 of human ERMAP (NP_061008.2).
Cell membrane, Cytoplasm, Single-pass type I membrane protein.
Calculated MW:
53kDa
Observed MW:
53kDa
The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
114625
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ERMAP antibody (CAB10425) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
