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Hemoglobin subunit alpha (HBA1) Rabbit Monoclonal Antibody (CAB9293)

SKU:
CAB9293
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Signal Transduction
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Hemoglobin subunit alpha (HBA1) Rabbit Monoclonal Antibody
SKU:CAB9293
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Hemoglobin subunit alpha (HBA1) (HBA1) (P69905).
Sequence:MVLS PADK TNVK AAWG KVGA HAGE YGAE ALER MFLS FPTT KTYF PHFD LSHG SAQV KGHG KKVA DALT NAVA HVDD MPNA LSAL SDLH AHKL RVDP VNFK
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:HBH; ECYT7; HBA-T3; METHBA; Hemoglobin subunit alpha (HBA1)
Positive Sample:Rat liver
Conjugate:Unconjugated
Cellular Localization:blood microparticle, cytosol, extracellular exosome, extracellular region, extracellular space, hemoglobin complex
Calculated MW:15kDa
Observed MW:11kDa

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Purification Method:Affinity purification
Gene ID:3039
Clone Number:ARC1510
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat liver, using Hemoglobin subunit alpha (HBA1) (HBA1) Rabbit mAb (CAB9293) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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