Hsc70-interacting protein (HIP) Monoclonal Antibody (CAB9567)
The Hsc70-interacting protein (HIP) Monoclonal Antibody (CAB9567) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, specifically targets the HIP protein, which plays a crucial role in regulating the activity of Hsc70, a molecular chaperone involved in protein folding and quality control.The HIP antibody is highly reactive with human samples and has been validated for use in Western blot applications, making it suitable for protein interaction studies in various cell types. By detecting and analyzing the HIP protein, researchers can gain insights into how it influences the function of Hsc70 and its impact on cellular pathways.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
Hsc70-interacting protein (HIP) Monoclonal Antibody
SKU:
CAB9567
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC1639
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method
Affinity purification
Gene ID
6767
RRID
AB_2863728
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Hsc70-interacting protein (HIP) Rabbit mAb (CAB9567) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Western blot analysis of various lysates, using Hsc70-interacting protein (HIP) Rabbit mAb (CAB9567) at 1 : 1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
