Human ACSF2 Recombinant Protein (RPPB5782)
- SKU:
- RPPB5782
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96CM8
- Research Area:
- Enzymes
Description
| Product Name: | Human ACSF2 Recombinant Protein |
| Product Code: | RPPB5782 |
| Size: | 20µg |
| Species: | Human |
| Target: | ACSF2 |
| Synonyms: | Acyl-CoA Synthetase Family Member 2, PPARG Binding, LongChain Fatty Acid Acyl Co-A Ligase Like, Acyl-CoA Synthetase Family Member 2,Mitochondrial, EC 6.2.1.26, EC 6.2.1.-, FLJ20920, EC 6.2.1, AVYV493, ACSMW, Acyl-CoAsynthetase family member 2, mitochondrial. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | ACSF2 protein solution (0.5mg/ml) containing PhosphateBuffered Saline pH 7.4 and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSLSSREVD RMVSTPIGGL SYVQGCTKKH LNSKTVGQCL ETTAQRVPEREALVVLHEDV RLTFAQLKEE VDKAASGLLS IGLCKGDRLG MWGPNSYAWV LMQLATAQAG IILVSVNPAYQAMELEYVLK KVGCKALVFP KQFKTQQYYN VLKQICPEVE NAQPGALKSQ RLPDLTTVIS VDAPLPGTLLLDEVVAAGST RQHLDQLQYN QQFLSCHDPI NIQFTSGTTG SPKGATLSHY NIVNNSNILG ERLKLHEKTPEQLRMILPNP LYHCLGSVAGTMMCLMYGAT LILASPIFNG KKALEAISRE RGTFLYGTPT MFVDILNQPDFSSYDISTMC GGVIAGSPAP PELIRAIINK INMKDLVVAY GTTENSPVTF AHFPEDTVEQ KAESVGRIMPHTEARIMNME AGTLAKLNTP GELCIRGYCV MLGYWGEPQK TEEAVDQDKW YWTGDVATMN EQGFCKIVGRSKDMIIRGGE NIYPAELEDF FHTHPKVQEV QVVGVKDDRM GEEICACIRL KDGEETTVEE IKAFCKGKISHFKIPKYIVF VTNYPLTISG KIQKFKLREQ MERHLNL |
Acyl-CoA synthetase family member 2, also known as ACSF2 is a member ofthe ATP-dependent AMP-binding enzyme family. Acyl-CoA synthetases are a familyof enzymes which catalyze the thioesterification of fatty acids withcoenzymeA to form activated intermediates, which play a basic part in lipidmetabolism as well as homeostasis of lipid-related processes. ACSF2 is requiredfor the complex of lipid synthesis, energy production via beta-oxidation,protein acylation and fatty-acid dependent transcriptional regulation.Moreover, ACSF2 is required for fatty acid import into cells by the process ofvectorial acylation.
ACSF2 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 597 amino acids (42-615 a.a) andhaving a molecular mass of 66.1kDa.ACSF2 is fused to a 23amino acid His-tag at N-terminus & purified by proprietary chromatographictechniques.
| UniProt Protein Function: | ACSF2: Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipodyte differentiation. Belongs to the ATP-dependent AMP-binding enzyme family.Protein type: Ligase; EC 6.2.1.-Chromosomal Location of Human Ortholog: 17q21.33Cellular Component: mitochondrionMolecular Function: ATP binding; ligase activityBiological Process: fatty acid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96CM8 |
| NCBI GenInfo Identifier: | 166198367 |
| NCBI Gene ID: | 80221 |
| NCBI Accession: | Q96CM8.2 |
| UniProt Secondary Accession: | Q96CM8,Q9H7G2, B4DFQ6, B4DHT5, B4DUF5 |
| UniProt Related Accession: | Q96CM8 |
| Molecular Weight: | |
| NCBI Full Name: | Acyl-CoA synthetase family member 2, mitochondrial |
| NCBI Synonym Full Names: | acyl-CoA synthetase family member 2 |
| NCBI Official Symbol: | ACSF2�� |
| NCBI Official Synonym Symbols: | ACSMW; AVYV493�� |
| NCBI Protein Information: | acyl-CoA synthetase family member 2, mitochondrial; PPARG binding, long chain fatty acid acyl Co-A ligase like |
| UniProt Protein Name: | Acyl-CoA synthetase family member 2, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | Acyl-CoA synthetase family |
| UniProt Gene Name: | ACSF2�� |
| UniProt Entry Name: | ACSF2_HUMAN |
