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APC Anti-Human CD127/IL-7RA Antibody [A019D5] (AGEL1784)

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SKU AGEL1784
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone A019D5
Conjugation APC
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Description

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APC Anti-Human CD127/IL-7RA Antibody [A019D5]

The Human CD127 (IL-7RA) Monoclonal Antibody (APC-conjugated, AGEL1784) from AssayGenie is a vital tool for immunology research focusing on the CD127 protein, which plays a crucial role in immune responses and lymphocyte development. This monoclonal antibody is specifically designed for flow cytometry applications, enabling precise detection and analysis of CD127 expression in various human cell types.CD127, also known as interleukin-7 receptor alpha, is fundamental for the survival and proliferation of T cells and plays a pivotal role in immune system function.

By targeting CD127, researchers can investigate its involvement in conditions such as autoimmune diseases, infectious diseases, and cancer, gaining insights into potential therapeutic targets and diagnostic markers.With its high specificity and sensitivity, the Human CD127 (IL-7RA) Monoclonal Antibody (APC-conjugated, AGEL1784) offers researchers a reliable tool for studying the complex mechanisms of immune responses and lymphocyte regulation. Trust AssayGenie for cutting-edge antibodies that enhance your immunology research endeavors.

Product Title:APC Anti-Human CD127/IL-7RA Antibody [A019D5]
SKU:AGEL1784
Size:20 Tests, 100 Tests, 200 Tests
Clone No:A019D5
Synonyms:Interleukin-7 receptor subunit alpha;IL-7RA;CDw127;CD127;IL-7Rα;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16871
Gene ID:3575
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

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