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APC Anti-Human CD58 Antibody [TS2/9.1] (AGEL1039)

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SKU AGEL1039
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone TS2/9.1
Conjugation APC
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Description

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APC Anti-Human CD58 Antibody [TS2/9.1]

The Human CD58 Monoclonal Antibody (APC Conjugated, TS2/9.1) is a valuable tool for research involving CD58, a cell adhesion molecule essential for immune responses. This antibody, derived from a hybridoma cell line, specifically targets human CD58 and is conjugated with APC for flow cytometry applications. It enables precise detection and analysis of CD58 expression on various cell types, making it ideal for studies in immunology and infectious diseases.CD58, also known as LFA-3, plays a crucial role in immune cell interactions by facilitating T cell adhesion and activation. Its involvement in immune synapse formation makes it a key player in adaptive immune responses and target identification for immune-based therapies.

Research on CD58 is essential for understanding immune cell communication and designing strategies for immunomodulation in diseases such as autoimmune disorders, infectious diseases, and transplant rejection.The Human CD58 Monoclonal Antibody (APC Conjugated, TS2/9.1) offers high specificity and sensitivity, providing reliable results for flow cytometry analysis of CD58 expression levels. With its potential applications in immunology and disease research, this antibody is a valuable resource for investigating the role of CD58 in immune regulation and immune-related disorders.

Product Title:APC Anti-Human CD58 Antibody [TS2/9.1]
SKU:AGEL1039
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS2/9.1
Synonyms:Lymphocyte function-associated antigen 3;CD58;Ag3;Surface glycoprotein LFA-3;LFA3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P19256
Gene ID:965
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.

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