Human ECHDC1 Recombinant Protein (RPPB1605)
- SKU:
- RPPB1605
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NTX5
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human ECHDC1 Recombinant Protein |
| Product Code: | RPPB1605 |
| Size: | 20µg |
| Species: | Human |
| Target: | ECHDC1 |
| Synonyms: | Ethylmalonyl-CoA decarboxylase, Enoyl-CoA hydratase domain-containing protein 1, Methylmalonyl-CoA decarboxylase, MMCD, ECHDC1, dJ351K20.2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The ECHDC1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 1mM DTT and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MALKQEMAKS LLKTASLSGR TKLLHQTGLS LYSTSHGFYE EEVKKTLQQF PGGSIDLQKE DNGIGILTLN NPSRMNAFSG VMMLQLLEKV IELENWTEGK GLIVRGAKNT FSSGSDLNAV KSLGTPEDGM AVCMFMQNTL TRFMRLPLIS VALVQGWALGGGAEFTTACD FRLMTPESKI RFVHKEMGII PSWGGTTRLV EIIGSRQALK VLSGALKLDS KNALNIGMVE EVLQSSDETK SLEEAQEWLK QFIQGPPEVI RALKKSVCSG RELYLEEALQ NERDLLGTVW GGPANLEAIA KKGKFNK |
Enoyl CoA hydratase domain containing 1 (ECHDC1) is a member of the enoyl-CoA hydratase/isomerase family. ECHDC1 is an enzyme which hydrates the double bond between the second and third carbons on acyl-CoA. The ECHDC1 enzyme is crucial to metabolizing fatty acids to supply both acetyl CoA and energy.
SNAP25 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 226 amino acids (1-206 a.a.) and having a molecular mass of 25.4 kDa. SNAP25 is fused to a 20 amino acid His Tag at N-terminus and purified by conventional chromatography techniques.
| UniProt Protein Function: | ECHDC1: Decarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activityx at lower level. Belongs to the enoyl-CoA hydratase/isomerase family. 6 isoforms of the human protein are produced by alternative splicing.Protein type: EC 4.1.1.41; EC 4.1.1.94Chromosomal Location of Human Ortholog: 6q22.33Cellular Component: cytosolMolecular Function: carboxy-lyase activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NTX5 |
| NCBI GenInfo Identifier: | 124007138 |
| NCBI Gene ID: | 55862 |
| NCBI Accession: | Q9NTX5.2 |
| UniProt Secondary Accession: | Q9NTX5,Q5TEF6, Q5TEF7, Q5TEG0, Q5TEG4, Q9NZ30, A6NFJ5 B7Z8S0, E9PEN7, E9PR31 |
| UniProt Related Accession: | Q9NTX5 |
| Molecular Weight: | 31,089 Da |
| NCBI Full Name: | Ethylmalonyl-CoA decarboxylase |
| NCBI Synonym Full Names: | ethylmalonyl-CoA decarboxylase 1 |
| NCBI Official Symbol: | ECHDC1�� |
| NCBI Official Synonym Symbols: | MMCD; HEL-S-76; dJ351K20.2�� |
| NCBI Protein Information: | ethylmalonyl-CoA decarboxylase |
| UniProt Protein Name: | Ethylmalonyl-CoA decarboxylase |
| UniProt Synonym Protein Names: | Enoyl-CoA hydratase domain-containing protein 1; Methylmalonyl-CoA decarboxylase (EC:4.1.1.41); MMCD |
| Protein Family: | Ethylmalonyl-CoA decarboxylase |
| UniProt Gene Name: | ECHDC1�� |
| UniProt Entry Name: | ECHD1_HUMAN |
