Human HDDC2 Recombinant Protein (RPPB1803)
- SKU:
- RPPB1803
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q7Z4H3
- Research Area:
- Enzymes
Description
| Product Name: | Human HDDC2 Recombinant Protein |
| Product Code: | RPPB1803 |
| Size: | 20µg |
| Species: | Human |
| Target: | HDDC2 |
| Synonyms: | HD Domain Containing 2, Hepatitis C Virus NS5A-Transactivated Protein 2, HCV NS5A-Transactivated Protein 2, C6orf74, NS5ATP2, Chromosome 6 Open Reading Frame 74, HD Domain-Containing Protein 2,DJ167O5.2, CGI-130, HDDC2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | HDDC2 protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMASVSSA TFSGHGARSL LQFLRLVGQL KRVPRTGWVY RNVQRPESVS DHMYRMAVMA MVIKDDRLNK DRCVRLALVH DMAECIVGDI APADNIPKEE KHRREEEAMK QITQLLPEDL RKELYELWEE YETQSSAEAK FVKQLDQCEM ILQASEYEDL EHKPGRLQDF YDSTAGKFNH PEIVQLVSEL EAERSTNIAA AASEPHS |
HD Domain Containing 2, also known as HDDC2 is a member of the HDDC2family. HDDC2 is an enzyme which contains one HD domain and it is expected toexhibit phosphohydrolase activity. It has been proposed that HDDC2 takes part innucleic acid metabolism, signal transduction and possibly other functions inbacteria, archaea and eukaryotes. The HD domain consists of highly conservedresidues, in particular histidines or aspartates. Porphyria cutanea tarda,Parkinson�s disease and Stickler syndrome have all been related with HDDC2.
HDDC2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a) and having a molecular mass of 25.8 kDa.HDDC2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | HDDC2: Belongs to the HDDC2 family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 6q13-q24.3Molecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q7Z4H3 |
| NCBI GenInfo Identifier: | 116875826 |
| NCBI Gene ID: | 51020 |
| NCBI Accession: | NP_057147 |
| UniProt Secondary Accession: | Q7Z4H3 |
| UniProt Related Accession: | Q7Z4H3 |
| Molecular Weight: | 18kDa |
| NCBI Full Name: | HD domain-containing protein 2 |
| NCBI Synonym Full Names: | HD domain containing 2 |
| NCBI Official Symbol: | HDDC2�� |
| NCBI Official Synonym Symbols: | C6orf74; CGI-130; NS5ATP2; dJ167O5.2�� |
| NCBI Protein Information: | HD domain-containing protein 2 |
| UniProt Protein Name: | HD domain-containing protein 2 |
| UniProt Synonym Protein Names: | Hepatitis C virus NS5A-transactivated protein 2; HCV NS5A-transactivated protein 2 |
| Protein Family: | HD domain-containing protein |
| UniProt Gene Name: | HDDC2�� |
| UniProt Entry Name: | HDDC2_HUMAN |
