Human IDI2 Recombinant Protein (RPPB1843)
- SKU:
- RPPB1843
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BXS1
- Research Area:
- Enzymes
Description
| Product Name: | Human IDI2 Recombinant Protein |
| Product Code: | RPPB1843 |
| Size: | 20µg |
| Species: | Human |
| Target: | IDI2 |
| Synonyms: | Isopentenyl-diphosphate Delta-isomerase 2, Isopentenyl pyrophosphate isomerase 2, IPP isomerase 2, IPPI2, IDI2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | IDI2 solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 1mM DTT and 0.1mM PMSF. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSDINLDWVD RRQLQRLEEM LIVVDENDKV IGADTKRNCH LNENIEKGLL HRAFSVVLFN TKNRILIQQR SDTKVTFPGY FTDSCSSHPL YNPAELEEKD AIGVRRAAQR RLQAELGIPG EQISPEDIVF MTIYHHKAKS DRIWGEHEIC YLLLVRKNVT LNPDPSETKS ILYLSQEELW ELLEREARGE VKVTPWLRTI AERFLYRWWP HLDDVTPFVE LHKIHRV |
Isopentenyl-diphosphate Delta-isomerase 2 (IDI2) is a member of the IPP isomerase type 1 family. IDI2 catalyzes the 1,3-allylic reorganization of the homoallylic substrate isopentenyl (IPP) to its extremely electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
IDI2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 247 amino acids (1-227 a.a.) and having a molecular mass of 28.9kDa.IDI2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | IDI2: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). Belongs to the IPP isomerase type 1 family. |
| UniProt Protein Details: | Protein type:Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 5.3.3.2; Isomerase Chromosomal Location of Human Ortholog: 10p15.3 Cellular Component: peroxisome; cytosol Molecular Function:hydrolase activity; metal ion binding; isopentenyl-diphosphate delta-isomerase activity Biological Process: isoprenoid biosynthetic process; isopentenyl diphosphate metabolic process; dimethylallyl diphosphate biosynthetic process; cholesterol biosynthetic process |
| UniProt Code: | Q9BXS1 |
| NCBI GenInfo Identifier: | 15147242 |
| NCBI Gene ID: | 91734 |
| NCBI Accession: | NP_150286.1 |
| UniProt Related Accession: | Q9BXS1 |
| Molecular Weight: | 26,753 Da |
| NCBI Full Name: | isopentenyl-diphosphate delta-isomerase 2 |
| NCBI Synonym Full Names: | isopentenyl-diphosphate delta isomerase 2 |
| NCBI Official Symbol: | IDI2�� |
| NCBI Official Synonym Symbols: | IPPI2�� |
| NCBI Protein Information: | isopentenyl-diphosphate delta-isomerase 2; IPP isomerase 2; diphosphate dimethylallyl diphosphate isomerase 2; isopentenyl pyrophosphate isomerase 2; isopentenyl-diphosphate Delta-isomerase 2 |
| UniProt Protein Name: | Isopentenyl-diphosphate delta-isomerase 2 |
| UniProt Synonym Protein Names: | Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2 |
| Protein Family: | Isopentenyl-diphosphate Delta-isomerase |
| UniProt Gene Name: | IDI2�� |
| UniProt Entry Name: | IDI2_HUMAN |
