Description
Human Oncostatin-M (OSM) ELISA Kit
The Human Oncostatin M (OSM) ELISA Kit is a reliable tool for accurately measuring levels of Oncostatin M in human biological samples. This kit offers high sensitivity and specificity, providing researchers with consistent and precise results for a variety of research applications.Oncostatin M is a cytokine that plays a critical role in inflammation, immune responses, and cell growth regulation. Dysregulation of Oncostatin M has been linked to various diseases such as cancer, inflammatory disorders, and autoimmune conditions.
Therefore, the measurement of Oncostatin M levels is essential for understanding the pathogenesis of these diseases and discovering potential therapeutic targets.With its user-friendly protocol and robust performance, the Human Oncostatin M (OSM) ELISA Kit is a valuable tool for researchers seeking to investigate the role of Oncostatin M in health and disease.
| Product Name: | Human Oncostatin-M (OSM) ELISA Kit |
| SKU: | HUEB0428 |
| Size: | 96T |
| Target: | Human Oncostatin-M (OSM) |
| Synonyms: | OSM |
| Assay Type: | Sandwich |
| Detection Method: | ELISA |
| Reactivity: | Human |
| Detection Range: | 0.156-10ng/mL |
| Sensitivity: | 0.054ng/mL |
| Intra CV: | 4.9% | ||||||||||||||||||||
| Inter CV: | 8.9% | ||||||||||||||||||||
| Linearity: |
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| Recovery: |
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| Function: | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. |
| Uniprot: | P13725 |
| Sample Type: | Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids |
| Specificity: | Natural and recombinant human Oncostatin-M |
| Research Area: | Immunology |
| Subcellular Location: | Secreted |
| Storage: | Please see kit components below for exact storage details |
| Note: | For research use only |
| UniProt Protein Function: | OSM: Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. Belongs to the LIF/OSM family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Cytokine Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: extracellular space Molecular Function:growth factor activity; oncostatin-M receptor binding; cytokine activity Biological Process: negative regulation of hormone secretion; multicellular organismal development; tyrosine phosphorylation of Stat3 protein; positive regulation of peptidyl-s |