Human PGM2 Recombinant Protein (RPPB2103)
- SKU:
- RPPB2103
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96G03
- Research Area:
- Enzymes
Description
| Product Name: | Human PGM2 Recombinant Protein |
| Product Code: | RPPB2103 |
| Size: | 20µg |
| Species: | Human |
| Target: | PGM2 |
| Synonyms: | Phosphoglucomutase 2, Glucose Phosphomutase 2, Phosphodeoxyribomutase,Phosphopentomutase, EC 5.4.2.2, PGM 2, Phosphoglucomutase-2, EC 5.4.2.7, EC5.4.2, MSTP006. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | PGM2 protein solution (1mg/ml) containing Phosphatebuffered saline (pH7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAAPEGS GLGEDARLDQ ETAQWLRWDK NSLTLEAVKR LIAEGNKEELRKCFGARMEF GTAGLRAAMG PGISRMNDLT IIQTTQGFCR YLEKQFSDLK QKGIVISFDA RAHPSSGGSSRRFARLAATT FISQGIPVYL FSDITPTPFV PFTVSHLKLC AGIMITASHN PKQDNGYKVY WDNGAQIISP HDKGISQAIE ENLEPWPQAWDDSLIDSSPL LHNPSASINN DYFEDLKKYC FHRSVNRETK VKFVHTSVHG VGHSFVQSAF KAFDLVPPEAVPEQKDPDPE FPTVKYPNPE EGKGVLTLSF ALADKTKARI VLANDPDADR LAVAEKQDSG EWRVFSGNEL GALLGWWLFT SWKEKNQDRS ALKDTYMLSS TVSSKILRAIALKEGFHFEE TLTGFKWMGN RAKQLIDQGK TVLFAFEEAI GYMCCPFVLD KDGVSAAVIS AELASFLATKNLSLSQQLKA IYVEYGYHIT KASYFICHDQ ETIKKLFENL RNYDGKNNYP KACGKFEISA IRDLTTGYDD SQPDKKAVLP TSKSSQMITF TFANGGVATM RTSGTEPKIKYYAELCAPPG NSDPEQLKKE LNELVSAIEE HFFQPQKYNL QPKAD |
PGM2or Phosphoglucomutase-2 is a protein of the alpha-d-phosphohexomutase family thatshares about 20% similarity with mammalian phosphoglucomutase 1. PGM2 Has lowglucose 1,6-bisphosphate synthase activity. Furthermore, PGM2 catalyzes theconversion of the nucleoside breakdown products ribose-1-phosphate anddeoxyribose-1-phosphate to the corresponding 5-phosphopentoses. In addition, PGM2 catalyzes theinterconversion of glucose-1-phosphate and glucose-6-phosphate.
PGM2 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 635 amino acids (1-612 a.a) andhaving a molecular mass of 70.7kDa. PGM2 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PGM2: Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity. Belongs to the phosphohexose mutase family. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - starch and sucrose; EC 5.4.2.2; EC 5.4.2.7; Isomerase Chromosomal Location of Human Ortholog: 4p14 Cellular Component: cytosol Molecular Function:phosphoglucomutase activity; phosphopentomutase activity; protein binding Biological Process: galactose catabolic process; glycogen biosynthetic process; glycogen catabolic process; pentose-phosphate shunt |
| UniProt Code: | Q96G03 |
| NCBI GenInfo Identifier: | 63055049 |
| NCBI Gene ID: | 55276 |
| NCBI Accession: | NP_060760 |
| UniProt Related Accession: | Q96G03 |
| Molecular Weight: | 67kDa |
| NCBI Full Name: | phosphoglucomutase-2 |
| NCBI Synonym Full Names: | phosphoglucomutase 2 |
| NCBI Official Symbol: | PGM2�� |
| NCBI Official Synonym Symbols: | MSTP006�� |
| NCBI Protein Information: | phosphoglucomutase-2 |
| UniProt Protein Name: | Phosphoglucomutase-2 |
| UniProt Synonym Protein Names: | Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphopentomutase (EC:5.4.2.7) |
| Protein Family: | Phosphoglucomutase |
| UniProt Gene Name: | PGM2�� |
| UniProt Entry Name: | PGM2_HUMAN |
