Human TREX2 Recombinant Protein (RPPB2350)
- SKU:
- RPPB2350
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BQ50
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human TREX2 Recombinant Protein |
| Product Code: | RPPB2350 |
| Size: | 25µg |
| Species: | Human |
| Target: | TREX2 |
| Synonyms: | Three Prime Repair Exonuclease 2, 3'-5' exonuclease TREX2 long form. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The TREX2 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 200mM NaCl, 5mM DTT and 30% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSEAPRAETF VFLDLEATGL PSVEPEIAEL SLFAVHRSSL ENPEHDESGA LVLPRVLDKL TLCMCPERPF TAKASEITGL SSEGLARCRK AGFDGAVVRT LQAFLSRQAG PICLVAHNGF DYDFPLLCAE LRRLGARLPR DTVCLDTLPA LRGLDRAHSH GTRARGRQGY SLGSLFHRYF RAEPSAAHSA EGDVHTLLLI FLHRAAELLA WADEQARGWA HIEPMYLPPD DPSLEA |
| UniProt Code: | Q9BQ50 |
TREX2 holds a 3-prime-to-5-prime exonuclease activity and eliminates mismatched, modified, fragmented, and normal nucleotides to produce the appropriate 3-prime termini for following steps in the DNA metabolic pathways. TREX2 has a role in DNA replication, repair, and recombination.
TREX2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 256 amino acids (1-236a.a.) and having a molecular mass of 28.0 kDa. TREX2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
