The Mouse CD106 Monoclonal Antibody (Biotin Conjugated) M/K-2.7 (AGEL0335) offered by Assay Genie is a valuable tool for researchers studying cell adhesion molecules and immune responses in mice. This monoclonal antibody specifically targets CD106, also known as vascular cell adhesion molecule-1 (VCAM-1), which plays a crucial role in immune cell recruitment and adhesion to vascular endothelium.With its biotin conjugation, this antibody provides versatility in experimental applications, allowing for easy detection and analysis of CD106 expression in various cell types. Whether investigating inflammation, vascular biology, or immune cell interactions, the Mouse CD106 Monoclonal Antibody offers reliable and reproducible results in techniques such as immunofluorescence, flow cytometry, and immunohistochemistry.
By targeting CD106, researchers can gain insights into the molecular mechanisms underlying immune cell trafficking and inflammatory responses, paving the way for advancements in immunology, cardiovascular research, and therapeutic development. Trust Assay Genie's reputable antibody for high-quality data and impactful discoveries in your studies of CD106 and related biological processes in mouse models.
Product Title:
Biotin Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:
AGEL0335
Size:
25µg, 100µg
Clone No:
M/K-2.7
Synonyms:
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
Biotin Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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