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PE/Cyanine5 Anti-Mouse CD11a Antibody [FD441.8] (AGEL0834)

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SKU AGEL0834
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone FD441.8
Conjugation PE/Cy5
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Description

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PE/Cyanine5 Anti-Mouse CD11a Antibody [FD441.8]

The Mouse CD11a Monoclonal Antibody PE-Cyanine5 Conjugated (FD441.8) is a powerful tool for researchers studying immune cell interactions and inflammatory responses. This antibody specifically targets CD11a, a cell surface protein involved in adhesion and signaling processes essential for immune cell function.By conjugating with PE-Cyanine5, this monoclonal antibody allows for precise detection and analysis of CD11a expression in a variety of cell types, enabling researchers to explore its role in immune responses in depth. The high specificity and reactivity of this antibody make it a reliable choice for flow cytometry and other immunological assays.CD11a is a key component of the integrin receptor lymphocyte function-associated antigen 1 (LFA-1), which facilitates immune cell adhesion and migration.

Understanding the regulation and function of CD11a in immune responses is crucial for unraveling the mechanisms of various diseases, including autoimmune disorders, inflammatory conditions, and infectious diseases.Researchers in immunology, cancer biology, and inflammation studies will find the Mouse CD11a Monoclonal Antibody PE-Cyanine5 Conjugated (FD441.8) indispensable for their investigations into immune cell behavior and the development of potential therapeutic strategies targeting CD11a. Validated for its efficacy and specificity, this antibody is a valuable asset for unlocking the mysteries of immune system function.

Product Title:PE/Cyanine5 Anti-Mouse CD11a Antibody [FD441.8]
SKU:AGEL0834
Size:25µg, 100µg
Clone No:FD441.8
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P24063
Gene ID:16408
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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