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PE/Cyanine5 Anti-Mouse CD3 Antibody [17A2] (AGEL0659)

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SKU AGEL0659
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 17A2
Conjugation PE/Cy5
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Description

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PE/Cyanine5 Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (PE-Cyanine5 Conjugated, 17A2) is a cutting-edge tool designed for researchers studying immune responses and cell surface markers in mouse models. This antibody, derived from hybridoma cells, is specifically engineered to target the CD3 protein, a crucial component of the T-cell receptor complex involved in T-cell activation and signaling.With its high specificity and sensitivity, this antibody is ideal for flow cytometry applications, allowing for precise identification and analysis of T cells in different experimental settings.

Its PE-Cyanine5 conjugation provides excellent fluorescence properties, enabling clear and accurate detection of CD3-expressing cells for detailed immunophenotyping studies.The CD3 Monoclonal Antibody (PE-Cyanine5 Conjugated, 17A2) opens up new avenues for research into immune responses, autoimmune diseases, and immunotherapy strategies in mouse models. By elucidating the role of CD3 in T-cell function and regulation, researchers can gain valuable insights into immune system dynamics and potential therapeutic targets for various diseases.

Product Title:PE/Cyanine5 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0659
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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