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FITC Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1281)

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SKU AGEL1281
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone IM7
Conjugation FITC
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Description

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FITC Anti-Human/Mouse CD44 Antibody [IM7]

The FITC-conjugated Mouse/Human CD44 Monoclonal Antibody (IM7) is a versatile tool for researchers studying the CD44 cell surface glycoprotein involved in cell-cell interactions, adhesion, and migration. This monoclonal antibody, conjugated with FITC for easy detection, is suitable for flow cytometry and fluorescence microscopy applications in both mouse and human samples.CD44 is a widely studied molecule with diverse functions in tissue development, inflammation, and cancer progression. Its expression is often altered in various pathological conditions, making it a valuable marker for identifying and characterizing specific cell populations.

The IM7 antibody specifically targets CD44, allowing for precise detection and analysis of CD44-expressing cells in research areas such as cancer biology, stem cell research, and immunology.With its high specificity and sensitivity, the FITC-conjugated Mouse/Human CD44 Monoclonal Antibody (IM7) from Assay Genie provides researchers with a reliable tool to advance their understanding of CD44 biology and its implications in various physiological and pathological processes.

Product Title:FITC Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1281
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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