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Anti-OTUD5 Antibody (CAB20516)

SKU:
CAB20516
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
DUBA
MCAND
€359
Frequently bought together:

Description

Product Name:OTUD5 Rabbit pAb
Product Code:CAB20516
Size:50uL, 100uL
Synonyms:DUBA, MCAND
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 362-571 of human OTUD5 (NP_060072.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 362-571 of human OTUD5 (NP_060072.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:55593
Uniprot:Q96G74
Calculated MW:60kDa
Observed MW:Refer to figures
UniProt Protein Function:OTUD5: a protein of unknown function. Contains a OTU-like cysteine protease domain. Protein type: Ubiquitin-specific protease; Protease; EC 3.4.19.12 Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytosol Molecular Function: ubiquitin-specific protease activity Biological Process: innate immune response; response to lipopolysaccharide; proteolysis; negative regulation of interferon type I production
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
UniProt Code:Q96G74
NCBI GenInfo Identifier:209977019
NCBI Gene ID:55593
NCBI Accession:NP_001129629.1
UniProt Secondary Accession:Q96G74,Q4KMN9, Q8N6T5, Q9H650, Q9H9U0, Q9NT65, B4DGG7 G5E9D7
UniProt Related Accession:Q96G74
Molecular Weight:
NCBI Full Name:OTU domain-containing protein 5 isoform b
NCBI Synonym Full Names:OTU deubiquitinase 5
NCBI Official Symbol:OTUD5  
NCBI Official Synonym Symbols:DUBA  
NCBI Protein Information:OTU domain-containing protein 5; OTU domain containing 5; deubiquinating enzyme A; deubiquitinating enzyme A
UniProt Protein Name:OTU domain-containing protein 5
UniProt Synonym Protein Names:Deubiquitinating enzyme A; DUBA
Protein Family:
UniProt Gene Name:OTUD5  
UniProt Entry Name:OTUD5_HUMAN

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