The Parva Polyclonal Antibody is a key tool for researchers studying Parva, a protein involved in cell adhesion and migration processes. This antibody, produced in rabbits, is highly specific to human Parva and is validated for use in various applications, including Western blotting. By binding to the Parva protein, researchers can accurately detect and analyze its expression in different cell types, making it an essential tool for studies in cell biology and cancer research.Parva, also known as alpha-actinin-1, plays a crucial role in maintaining cell structure and facilitating cell movement. Its involvement in cell adhesion and cytoskeletal organization makes it a target of interest for research on processes such as cell migration and invasion.
Understanding the function of Parva is essential for uncovering its role in diseases like cancer and neurological disorders, where aberrant cell movement plays a significant role in disease progression.Overall, the Parva Polyclonal Antibody is a valuable resource for researchers seeking to delve deeper into the mechanisms underlying cell adhesion and migration, with potential implications for the development of novel therapeutic approaches targeting these processes.
Product Name:
PARVA Polyclonal Antibody
SKU:
CAB24474
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PARVA (NP_060692.3) .
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.
Purification Method:
Affinity purification
Gene ID:
55742
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PARVA Rabbit pAb (CAB24474) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
