The RBM20 Polyclonal Antibody is a valuable tool for researchers studying RBM20, a key RNA-binding protein involved in regulating alternative splicing in the heart. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting the RBM20 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it indispensable for research in cardiology and molecular biology.
RBM20 is known for its crucial role in maintaining cardiac function and is implicated in various cardiovascular conditions, including dilated cardiomyopathy. By investigating the function and regulation of RBM20, researchers can gain valuable insights into the molecular mechanisms underlying heart disease and potentially develop novel therapeutic strategies. This antibody is an essential tool for studying RBM20 and its impact on cardiac health and disease progression.
Product Name:
RBM20 Polyclonal Antibody
SKU:
CAB22117
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 820-980 of human RBM20 (NP_001127835.2).
This gene encodes a protein that binds RNA and regulates splicing. Mutations in this gene have been associated with familial dilated cardiomyopathy.
Purification Method:
Affinity purification
Gene ID:
282996
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RBM20 Rabbit pAb (CAB22117) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
