Defensins are cationic peptides that are an important component of the innate immune response. Some leukocytes and epithelial surfaces express beta-defensins. Human beta-defensins include BD-1, BD-2, BD-3, and BD-4. The beta-defensins are characterized by a six-cysteine motif, which leads to three intra-molecular disulfide bonds. Beta-defensins attract immature dendritic cells and memory T cells as well. The C-terminal portion of precursor proteins is transcribed as beta-defensins; they are generated via proteolytic cleavage of a signaling sequence. Human DEFB104A Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Recombinant Human beta-Defensin 4 is produced by our E.coli expression system and the target gene encoding Glu23-Pro72 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
6.0 kDa
AP Mol Mass:
9 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 130mM NaCl, pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
