The RRAGC Polyclonal Antibody (CAB7479) is a valuable tool for researchers studying RRAGC, a key protein involved in the mTORC1 signaling pathway. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the RRAGC protein, this antibody enables the detection and analysis of RRAGC in various cell types, making it ideal for investigations in cell biology, metabolism, and cancer research.RRAGC is a critical regulator of mTORC1 activation, which plays a central role in cell growth, metabolism, and autophagy. Dysregulation of the mTORC1 pathway has been linked to various diseases, including cancer, metabolic disorders, and neurodegenerative conditions.
Therefore, understanding the function of RRAGC is essential for developing targeted therapies that modulate mTORC1 activity in these pathological contexts.By utilizing the RRAGC Polyclonal Antibody, researchers can gain valuable insights into the role of RRAGC in cellular signaling pathways and disease progression. Its high specificity and reliability make it a valuable tool for advancing our understanding of mTORC1 regulation and potential therapeutic interventions.
Product Name:
RRAGC Rabbit Polyclonal Antibody
SKU:
CAB7479
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human RRAGC (NP_071440.1).
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
64121
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RRAGC antibody (CAB7479) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
