The Alpha-1 Antitrypsin (SERPINA1) Antibody (CAB12481) is a high-quality antibody developed for reliable detection and analysis of target proteins. Developed using rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding specifically to the Serpina1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable asset for studies in immunology, inflammation, and disease research.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Alpha-1 Antitrypsin (SERPINA1) Antibody
SKU:
CAB12481
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.
Purification Method
Affinity purification
Gene ID
5265
RRID
AB_2759324
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Alpha-1 Antitrypsin (SERPINA1) Rabbit pAb (CAB12481) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Immunofluorescence analysis of PC-12 cells using Alpha-1 Antitrypsin (SERPINA1) Rabbit pAb (CAB12481) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
