The TFEB Monoclonal Antibody (CAB21927) is a powerful tool for studying TFEB, a transcription factor known for its role in regulating lysosomal biogenesis and autophagy. This monoclonal antibody, raised in mice, is highly specific for TFEB and has been validated for use in various applications, including immunofluorescence and immunohistochemistry.TFEB is a key player in cellular processes that are crucial for maintaining cellular homeostasis and responding to stress. Dysregulation of TFEB has been implicated in various diseases, including neurodegenerative disorders and cancer.
By using the TFEB Monoclonal Antibody, researchers can gain valuable insights into the mechanisms by which TFEB regulates lysosomal function and autophagy, leading to potential therapeutic targets for treating these diseases.Overall, the TFEB Monoclonal Antibody is a reliable tool for researchers studying TFEB and its implications in various cellular processes and diseases. Its specificity and validated applications make it an essential component for studies in cell biology, neurology, and oncology.
Product Name:
TFEB Monoclonal Antibody
SKU:
CAB21927
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-173 of human TFEB (NP_009093.1).
Enables DNA-binding transcription factor activity; enzyme binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to amino acid starvation; lysosome localization; and positive regulation of autophagy. Located in cytosol; lysosomal membrane; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
7942
Clone Number:
ARC53778
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Mouse lung using TFEB Rabbit mAb (CAB21927) at dilution of 1:100(40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
