The TGS1 Antibody (CAB7848) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TGS1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and genetics research.TGS1 is an essential enzyme involved in the methylation of small nuclear RNAs, impacting various cellular processes such as RNA splicing and gene expression.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
TGS1 Antibody
SKU:
CAB7848
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PIMT, PIPMT, NCOA6IP, TGS1
Positive Sample:
Jurkat, MCF7, 293T, Mouse thymus, Mouse testis
Cellular Localization:
Cajal Body, Cytoplasm, Nucleus.
Calculated MW:
97kDa
Observed MW:
97kDa
Enables RNA trimethylguanosine synthase activity. Involved in 7-methylguanosine cap hypermethylation. Located in cytosol and nucleus.
Purification Method
Affinity purification
Gene ID
96764
RRID
AB_2772588
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using TGS1 Rabbit pAb (CAB7848) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.