Human CKMBITII Recombinant Protein (RPPB2484)
- SKU:
- RPPB2484
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human CKMBITII Recombinant Protein |
| Product Code: | RPPB2484 |
| Size: | 50µg |
| Species: | Human |
| Target: | CKMBITII |
| Synonyms: | Creatine Kinase MB Isoenzyme Type-II, CKMBITII, CKMBI, CKMB. |
| Source: | Pichia Pastoris |
| Physical Appearance: | Sterile Filtered colourless liquid formulation. |
| Formulation: | Each mg of protein contains 20mM Tris-HCl, pH-6.8, 1mM EDTA and 1mM DTT, 50% (v/v) glycerol. |
| Stability: | CKMBITII although stable at 15°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles. |
| Biological Activity: | The enzyme activity measured by kinetic assay at 340nm was 884.6 IU/mg at 37 degrees. |
CK-MB Type II possesses the naturally occurring carboxy-terminal amino acid lysine.This occurs during a myocardial infarct (MI or heart attack) when CK-MB Type II is released from damaged heart muscle, and the C-terminal lysine is cleaved in the blood stream, thus creating CK-MB Type I. This difference can be exploited in diagnosis of an MI.
CKMBITII Human Recombinant produced in Pichia Pastoris reacts with polyclonal antibodies to MB Isoenzyme in ELISA.
