Human POP7 Recombinant Protein (RPPB4280)
- SKU:
- RPPB4280
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O75817
Description
| Product Name: | Human POP7 Recombinant Protein |
| Product Code: | RPPB4280 |
| Size: | 10µg |
| Species: | Human |
| Target: | POP7 |
| Synonyms: | Ribonuclease P protein subunit p20, RNaseP protein p20, Ribonucleases P/MRP protein subunit POP7 homolog, hPOP7, POP7, RPP20, 0610037N12Rik, RPP2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | POP7 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 50% glycerol, 2mM DTT and 2mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSEFMAENR EPRGAVEAEL DPVEYTLRKR LPSRLPRRPN DIYVNMKTDF KAQLARCQKL LDGGARGQNA CSEIYIHGLG LAINRAINIA LQLQAGSFGS LQVAANTSTV ELVDELEPET DTREPLTRIR NNSAIHIRVF RVTPK |
Processing Of Precursor 7, also known as POP7, is a part of the histone-like Alba family. POP7 is a part of ribonuclease P which is a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. POP7 is also a part of RNase MRP complex, which cleaves pre-rRNA sequences.
POP7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids (1-140 a.a.) and having a molecular mass of 18.3kDa.POP7 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | POP7: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the histone-like Alba family. |
| UniProt Protein Details: | Protein type:Nucleolus; Ribonuclease; EC 3.1.26.5 Chromosomal Location of Human Ortholog: 7q22 Cellular Component: nucleolar ribonuclease P complex; nucleus Molecular Function:protein binding; ribonuclease P activity Biological Process: tRNA processing |
| UniProt Code: | O75817 |
| NCBI GenInfo Identifier: | 153791431 |
| NCBI Gene ID: | 10248 |
| NCBI Accession: | NP_005828.2 |
| UniProt Secondary Accession: | O75817,Q9BV74, A4D2E0, |
| UniProt Related Accession: | O75817 |
| Molecular Weight: | 42.7 kDa |
| NCBI Full Name: | ribonuclease P protein subunit p20 |
| NCBI Synonym Full Names: | processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) |
| NCBI Official Symbol: | POP7�� |
| NCBI Official Synonym Symbols: | RPP2; RPP20; 0610037N12Rik�� |
| NCBI Protein Information: | ribonuclease P protein subunit p20; hPOP7; RNaseP protein p20; ribonucleases P/MRP protein subunit POP7 homolog; processing of precursor 7, ribonuclease P subunit; POP7 (processing of precursor, S. cerevisiae) homolog |
| UniProt Protein Name: | Ribonuclease P protein subunit p20 |
| UniProt Synonym Protein Names: | Ribonucleases P/MRP protein subunit POP7 homolog; hPOP7 |
| Protein Family: | Ribonuclease P protein |
| UniProt Gene Name: | POP7�� |
| UniProt Entry Name: | POP7_HUMAN |
