The LY96 Antibody (CAB1866) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LY96 protein, this antibody enables detection and analysis in various cell types, making it ideal for studies related to immunology and infectious diseases.LY96, also known as MD-2, plays a crucial role in recognizing bacterial lipopolysaccharides and activating the immune response.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
LY96 Antibody
SKU:
CAB1866
Size:
20μL, 100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MD2, MD-2, ly-96, ESOP-1, LY96
Positive Sample:
Mouse liver, Mouse spleen, Mouse kidney
Cellular Localization:
Secreted, Extracellular Space.
Calculated MW:
19kDa
Observed MW:
25kDa
This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method
Affinity purification
Gene ID
23643
RRID
AB_2763900
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using LY96 Rabbit pAb (CAB1866) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.