The PPP1R9B Polyclonal Antibody (CAB17229) is a valuable tool for researchers studying PPP1R9B, a protein involved in various cellular processes, including cell motility and cytoskeletal organization. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By binding specifically to the PPP1R9B protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and neuroscience. PPP1R9B, also known as neurabin-2, plays a crucial role in the regulation of actin dynamics and synaptic plasticity, making it a key target for research on neuronal function and synaptic transmission.
Furthermore, PPP1R9B has been implicated in neurological disorders, such as Alzheimer's disease and schizophrenia, highlighting its potential as a therapeutic target in treating these conditions. Understanding the function of PPP1R9B can provide valuable insights into the mechanisms underlying these diseases and aid in the development of novel treatment strategies.
Product Name:
PPP1R9B Rabbit Polyclonal Antibody
SKU:
CAB17229
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PPP1R9B (NP_115984.3).
This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors.
Purification Method:
Affinity purification
Gene ID:
84687
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPP1R9B Rabbit pAb (CAB17229) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
