Tumor necrosis factor receptor superfamily member 3; also known as Lymphotoxin-beta receptor;Tumor necrosis factor C receptor;Tumor necrosis factor receptor 2-related protein;Tumor necrosis factor receptor type III;LTBR;TNFCR; TNFR3 and TNFRSF3; is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types; but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition; LTBR can lead to the release of the cytokine interleukin 8.
Product Name:
Human LTBR/TNFRSF3 Recombinant Protein (RPES3867)
Product Code:
RPES3867
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Tumor Necrosis Factor Receptor Superfamily Member 3, Lymphotoxin-Beta Receptor, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor 2-Related Protein, Tumor Necrosis Factor Receptor Type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TNFRSF3
Accession:
P36941
Sequence:
Gln31-Met227
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Lymphotoxin beta receptor is produced by our Mammalian expression system and the target gene encoding Gln31-Met227 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
48.8 kDa
AP Mol Mass:
61 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
