Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.
Product Name:
Human PLA2G16 Recombinant Protein (RPES0096)
Product Code:
RPES0096
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Group XVI Phospholipase A1/A2, Adipose-Specific Phospholipase A2, AdPLA, H-Rev 107 Protein Homolog, HRAS-Like Suppressor 1, HRAS-Like Suppressor 3, HRSL3, HREV107-1, HREV107-3, Renal Carcinoma Antigen NY-REN-65, PLA2G16, HRASLS3, HREV107
Accession:
P53816
Sequence:
Asp12-Asp132
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Phospholipase A2 Group XVI is produced by our E.coli expression system and the target gene encoding Asp12-Asp132 is expressed with a 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
15.9 kDa
AP Mol Mass:
15 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
