The MVD Monoclonal Antibody (CAB0813) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in a variety of applications, including Western blotting.MVD, also known as mevalonate diphosphate decarboxylase, plays a crucial role in the mevalonate pathway, which is essential for the production of cholesterol, steroid hormones, and other important molecules in the body.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
MVD Monoclonal Antibody
SKU:
CAB0813
Size:
20μL, 100μL
Reactivity:
Human, Rat
Clone Number:
ARC2541
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MPD, MDDase, POROK7, FP17780, MVD
Positive Sample:
Hep G2, Rat brain
Cellular Localization:
Cytosol.
Calculated MW:
43kDa
Observed MW:
43kDa
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
Purification Method
Affinity purification
Gene ID
4597
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MVD Rabbit mAb (CAB0813) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.