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For decades, immunologists believed that only adaptive immunity—the sophisticated system of T cells and B cells—could form lasting memories of past infections. The innate immune system, our body's first line of defense, was thought to be hardwired and incapable of learning. However, a groundbreaking discovery has shattered this dogma. Scientists have found that innate immune cells can indeed "remember" previous encounters with pathogens, a phenomenon called trained immunity. This memory doesn't rely on the genetic recombination that creates antibodies; instead, it's written into the very architecture of our chromosomes through epigenetic modifications and metabolic rewiring. The implications …