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The Role of CD25+FOXP3+CD45RA- Treg Cells in Cancer PrognosisIntroductionRegulatory T-cells (Treg cells) are a specialized subset of T-cells that play a pivotal role in maintaining immune homeostasis and tolerance. These cells are essential for preventing autoimmune diseases and controlling excessive immune responses. However, in the context of cancer, Treg cells have garnered significant attention due to their dual roles in promoting tumor angiogenesis and modulating antitumor immunity. This article delves into the prognostic significance of CD25+FOXP3+CD45RA- Treg cell infiltration in tumor specimens, highlighting their potential as biomarkers for cancer outcomes.Study SummaryIn a comprehe …

Understanding the EGFR Pathway and YAP in Non-Small Cell Lung CancerThe epidermal growth factor receptor (EGFR) pathway plays a pivotal role in the development and progression of non-small cell lung cancer (NSCLC). This article delves into the intricate relationship between the EGFR pathway, Yes-associated protein (YAP), and the tumor microenvironment, highlighting their implications for cancer progression and treatment strategies.IntroductionNon-small cell lung cancer (NSCLC) is one of the most prevalent forms of lung cancer, characterized by its aggressive nature and poor prognosis. The EGFR pathway is a well-established oncogenic pathway that significantly influences tumor growth and meta …