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For decades, we viewed cancer as a rogue army of cells, a biological glitch driven solely by genetic mutations and metabolic greed. We imagined tumors as isolated fortresses, growing in a vacuum of their own making. But a radical shift is underway. Scientists have discovered that tumors are not just passive lumps of tissue; they are active participants in the body’s most complex communication network: the nervous system. This is the dawn of cancer neuroscience. Introduction The field of oncology is currently undergoing a profound transformation as we move beyond a purely cell-centric view of malignancy. Historically, the nervous system was thought to be a bystander in the oncogenic process, …