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Japanese Encephalitis Antibodies, Proteins & ELISA Kits

Japanese Encephalitis Antibodies, Proteins & ELISA Kits | Assay Genie
Infectious Disease · Japanese encephalitis virus (JEV)

Japanese Encephalitis antibodies, proteins & ELISA kits

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus and a leading cause of viral encephalitis across Asia, maintained in a cycle involving Culex mosquitoes, pigs and wading birds.

JEVEnvelope / NS1Mosquito-borne
JEV
Flavivirus
Culex
Mosquito vector
Pigs / birds
Amplifying hosts
Vaccine
Available
Overview

What is Japanese Encephalitis?

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus and a leading cause of viral encephalitis across Asia, maintained in a cycle involving Culex mosquitoes, pigs and wading birds.

Most infections are asymptomatic but a minority cause severe encephalitis. Anti-JEV IgM/IgG serology and recombinant envelope/NS1 antigens support diagnosis and vaccine research.

Transmission & symptoms

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus spread by Culex species in an enzootic cycle involving pigs and wading birds. Most infections are silent, but a minority cause severe encephalitis with high mortality and neurological sequelae.

Diagnosis & serology

Diagnosis relies on anti-JEV IgM (typically in CSF or serum) and IgG serology, with recombinant envelope (E) and NS1 antigens used in ELISA. Flavivirus cross-reactivity is an important consideration in endemic regions.

Research applications

Research tools support JEV neuropathogenesis (blood-brain-barrier disruption via MMP-9, vimentin), neuroinflammatory cytokine responses and vaccine immunogenicity.

FAQs

Japanese Encephalitis — frequently asked questions

How is Japanese encephalitis diagnosed?
Detection of anti-JEV IgM in CSF or serum by capture ELISA is the mainstay, supported by IgG and molecular testing where available.
Is there a vaccine for JEV?
Yes — effective JE vaccines exist; recombinant envelope and NS1 antigens support immunogenicity and serodiagnostic research.
Why can JEV serology be tricky?
JEV shares antigens with other flaviviruses (dengue, West Nile), so cross-reactivity must be controlled for in endemic settings.
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