Description
PD-1/CD279 Polyclonal Antibody (CAB23886)
The PD-1 (CD279) Polyclonal Antibody (CAB23886) is a valuable tool for researchers studying the programmed cell death protein 1 (PD-1), a cell surface receptor crucial for regulating immune responses. This antibody, produced in rabbits, is highly specific for human samples and is ideal for use in Western blot experiments. By targeting the PD-1 protein, researchers can accurately measure and analyze its expression in various cell types, providing insights into its role in immunology and cancer research.
PD-1, also known as programmed death-1 receptor, is a key player in immune checkpoint regulation, controlling T cell activation and preventing autoimmune responses. Dysregulation of PD-1 has been implicated in diseases like cancer, chronic infections, and autoimmune disorders, making it an attractive target for therapeutic interventions. By studying PD-1 with this antibody, researchers can uncover new insights into its function and potential therapeutic applications in immunotherapy.
| Product Name: | PD-1/CD279 Polyclonal Antibody |
| Product Code: | CAB23886 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | EL4, Mouse thymus, Mouse spleen |
Involved in negative regulation of immune response. Acts upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in external side of plasma membrane. Is expressed in retina. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1).
| Immunogen: | Recombinant protein of mouse PD-1/CD279. |
| Sequence: | Email for sequence |
| Synonyms: | PD-1, Pdc1, Ly101 |
| Calculated MW: | 32kDa |
| Observed MW: | 61kDa |
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