Description
PI3K / AKT / mTOR Antibody Sampler Pack
The PI3K / AKT / mTOR Antibody Sampler Pack from Assay Genie brings together 8 rigorously validated antibodies spanning the key nodes of the PI3K / AKT / mTOR pathway. Each antibody is supplied in a convenient 20µL trial size, letting researchers screen an entire signalling axis in a single, cost-effective pack before committing to full-size vials — ideal for pathway mapping, target validation and multi-marker studies.
The PI3K-AKT-mTOR axis is a central regulator of cell growth, metabolism and survival. Growth-factor signalling activates PI3K to generate PIP3 and recruit AKT, which is fully activated by phosphorylation at Thr308 and Ser473; downstream mTOR, p70 S6K and 4E-BP1 control protein synthesis. PTEN antagonises the pathway and is a frequently lost tumour suppressor.
All antibodies are individually quality-controlled and validated for applications including ELISA, IF/ICC, IHC-P, IP, WB, with reactivity across human, mouse and rat where indicated. Every target is also available in a full 100µL size for scale-up.
| Target | Antibody | Cat. No. | Host | Reactivity | Applications | Size |
| PI3K p85 | Anti-PI3 Kinase p85 beta [ARC0287] Monoclonal Antibody | CAB4860-20 | Rabbit | Human, Mouse, Rat | WBELISA | 20µL |
| PTEN | Anti-PTEN [ARC0364] Monoclonal Antibody | CAB21892-20 | Rabbit | Human, Mouse, Rat | WBELISA | 20µL |
| AKT (pan) | Anti-AKT1 [ARC51585] Monoclonal Antibody | CAB22770-20 | Rabbit | Human, Mouse, Rat | WBIHC-PIF/ICCELISA | 20µL |
| Phospho-AKT S473 | Anti-Phospho-AKT1-S473 [ARC0169] Monoclonal Antibody | CABP0637-20 | Rabbit | Human, Mouse, Rat | WBIHC-PELISA | 20µL |
| mTOR | Anti-mTOR Polyclonal Antibody | CAB2445-20 | Rabbit | Human, Mouse, Rat | WBIF/ICCIPELISA | 20µL |
| Phospho-mTOR | Anti-Phospho-mTOR-S2448 [ARC0094] Monoclonal Antibody | CABP0115-20 | Rabbit | Human, Mouse, Rat | WBELISA | 20µL |
| p70 S6K | Anti-p70 S6 Kinase 1 [ARC57223] Monoclonal Antibody | CAB4898-20 | Rabbit | Human, Mouse, Rat | WBIHC-PELISA | 20µL |
| 4E-BP1 | Anti-eIF4EBP1 Antibody -Knockout Validated | CAB1248-20 | Rabbit | Human, Mouse, Rat | WBIHC-PIF/ICCELISA | 20µL |
The PI3K-AKT-mTOR axis is a central regulator of cell growth, metabolism and survival. Growth-factor signalling activates PI3K to generate PIP3 and recruit AKT, which is fully activated by phosphorylation at Thr308 and Ser473; downstream mTOR, p70 S6K and 4E-BP1 control protein synthesis. PTEN antagonises the pathway and is a frequently lost tumour suppressor.
| Specification | Detail |
| Pack Format | 8 antibodies, 20µL each (trial size) |
| Storage | Store at -20°C upon receipt |
| Shelf Life | 12 months from date of receipt |
| Shipping | Gel pack |
| Scale-up | Every antibody is also available individually in a full 100µL size |