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Understanding Lag-3, Tim-3, and TIGIT: Key Players in T Cell RegulationThe immune system's ability to regulate T cell responses is crucial for maintaining homeostasis and combating diseases such as cancer and autoimmune disorders. Co-inhibitory receptors, including Lag-3, Tim-3, and TIGIT, play specialized roles in this regulation. This article explores their functions and potential as therapeutic targets in cancer treatment, drawing insights from recent research.Study SummaryRecent studies have highlighted the importance of co-inhibitory receptors in T cell regulation. Lag-3 (LAG3), Tim-3 (TIM3), and TIGIT (TIGIT) are integral to the immune checkpoint pathways that modulate T cell activatio …

Exploring LAG-3: A Key Regulator in T Cell ImmunityLAG-3 (Lymphocyte Activation Gene-3) is an inhibitory receptor that plays a crucial role in modulating T cell activation and effector functions. This article delves into the multifaceted role of LAG-3, highlighting its implications in cancer and autoimmune diseases, and discusses how Assay Genie tools can facilitate research in this area.IntroductionLAG-3 is a cell surface receptor that has garnered significant attention in immunology due to its inhibitory effects on T cell responses. By understanding LAG-3 signaling, researchers can better comprehend its role in immune regulation, particularly in the context of cancer and autoimmune disease …