MAPK / ERK Pathway Antibody Sampler Pack

MAPK / ERK Pathway Antibody Sampler Pack

The MAPK / ERK Pathway Antibody Sampler Pack from Assay Genie brings together 8 rigorously validated antibodies spanning the key nodes of the MAPK / ERK Pathway pathway. Each antibody is supplied in a convenient 20µL trial size, letting researchers screen an entire signalling axis in a single, cost-effective pack before committing to full-size vials — ideal for pathway mapping, target validation and multi-marker studies.

The RAS-RAF-MEK-ERK cascade transduces growth-factor and oncogenic signals from receptor tyrosine kinases to the nucleus. Sequential phosphorylation of RAF, MEK1/2 and ERK1/2 culminates in activation of transcription factors such as Elk-1 and p90RSK, controlling proliferation, differentiation and survival; the pathway is among the most frequently dysregulated in human cancer.

All antibodies are individually quality-controlled and validated for applications including ELISA, IF/ICC, IHC-P, IP, WB, with reactivity across human, mouse and rat where indicated. Every target is also available in a full 100µL size for scale-up.

The RAS-RAF-MEK-ERK cascade transduces growth-factor and oncogenic signals from receptor tyrosine kinases to the nucleus. Sequential phosphorylation of RAF, MEK1/2 and ERK1/2 culminates in activation of transcription factors such as Elk-1 and p90RSK, controlling proliferation, differentiation and survival; the pathway is among the most frequently dysregulated in human cancer.