Recombinant SARS-CoV-2 NSP10 Protein (His Tag) (RPES0007)

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SKU:
RPES0007
€300

Description

Background

Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.
Information Description
Product Name:
SARS-Cov-2 NSP10 Protein (His Tag)
Size:

10µg

SKU:

RPES0007

Activity:
Synonym:
SARS-CoV 2 nsp10; SARS-CoV 2 Growth factor-like peptide; SARS-CoV 2 GFL
Protein Construction:
SARS-Cov-2 NSP10 is produced by our E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with a 6His tag at the N-terminus.
Sequence:
Ala1-Gln139
Fusion tag:
N-6His
Accession:
YP_009725306.1
Species:

Virus

Expressed Host:
E.coli
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Purity:
> 80 % as determined by reducing SDS-PAGE.
Endotoxin:
< 1.0 EU per µg as determined by the LAL method.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass:
17.9 kDa
AP Mol Mass:
18 kDa
Formulation:
Supplied as a 0.2 uM filtered solution of PBS, 10% Glycerol, pH 7.4.
Reconstitution:
Please refer to the printed manual for detailed information.
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