Description
Cell Cycle - G1/S Antibody Sampler Pack (ABSP006)
The Cell Cycle - G1/S Antibody Sampler Pack from Assay Genie brings together 8 rigorously validated antibodies covering the key nodes of this pathway in a convenient 20µL trial format. It is designed to let researchers interrogate an entire signalling axis in a single, cost-effective pack, then scale up to full-size formats for the targets that matter most to their work.
| Pack Name: | Cell Cycle - G1/S Antibody Sampler Pack |
| SKU: | ABSP006 |
| Research Area: | Cancer |
| Targets Included: | 8 |
| Format: | 8 × 20µL |
| Targets: | Cyclin D1, Cyclin E1, CDK4, CDK6, Rb, Phospho-Rb, p21, p27 |
| Target | Antibody | SKU | Host | Reactivity | Applications | Size |
|---|---|---|---|---|---|---|
| Cyclin D1 | Anti-Cyclin D1 Antibody | CAB11022-20 | Rabbit | Human, Mouse, Rat | WB IHC-P IF/ICC IP ELISA | 20µL |
| Cyclin E1 | Anti-Cyclin E1 [ARC51383] Monoclonal Antibody | CAB22360-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
| CDK4 | Anti-CDK4 [ARC51004] Monoclonal Antibody -Knockout Validated | CAB11136-20 | Rabbit | Human, Mouse, Rat, Monkey | WB IHC-P ELISA | 20µL |
| CDK6 | Anti-CDK6 [ARC0224] Monoclonal Antibody | CAB0106-20 | Rabbit | Human, Rat | WB ELISA | 20µL |
| Rb | Anti-RB Monoclonal Antibody | CAB28033-20 | Rabbit | Human | WB IP IHC-P ELISA | 20µL |
| Phospho-Rb | Anti-Phospho-RB-S780 [ARC0096] Monoclonal Antibody | CABP0117-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
| p21 | Anti-CDKN1A Antibody | CAB20471-20 | Rabbit | Mouse, Rat | WB ELISA | 20µL |
| p27 | Anti-CDKN1B/p27KIP1 Antibody -Knockout Validated | CAB16633-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
Progression through the G1/S restriction point is driven by cyclin D-CDK4/6 and cyclin E-CDK2 complexes, which phosphorylate Rb to release E2F transcription factors. CDK inhibitors p21 and p27 restrain this transition, integrating mitogenic and stress signals that are commonly deregulated in cancer.
| Pack Format: | 8 antibodies, 20µL each (trial size) |
| Storage: | Store at -20°C |
| Shelf Life: | 12 months |
| Shipping: | Gel pack |
Every antibody in this sampler pack is also available individually in full 100µL size for follow-on experiments and assay scale-up.